Systemic lupus erythematosus (SLE) is an autoimmune disorder or disease of the immune system that causes acute and chronic inflammation to various body parts such as kidney, brain, heart, lungs and blood cells. It occurs when the immune system dysfunction and attacks its own tissues causing inflammation.
Causes Of Systemic Lupus Erythematosus The exact cause of developing SLE is unknown. But there are several factors, which in combination, can cause it. Researchers believe that a family with a history of lupus are at higher risk. Their gene may combine with some environmental factors and trigger lupus. However, the study needs more research as there is only 10 per cent of SLE patients whose close relatives also have the condition.  Other factors include:
UV rays of the sun
Symptoms Of Systemic Lupus Erythematosus
Symptoms of SLE are very confusing as two patients with the same condition may not have the same symptoms. Some may have mild symptoms while some may have severe; in some people it may develop slowly while in others, it may flare fast. Also, in some, the symptoms may go after some time while in some it may get chronic. Common symptoms include:
Rash on the face on the cheeks and nose (like a butterfly) 
Fever Loss of appetite
Ulcer in the mouth or nose